Sensorium: the original raison d'etre of the motile cilium?

Spreading the practice of evidence-based medicine: MetaStar's raison d'etre.

A finite elements study on the role of primary cilia in sensing mechanical stimuli to cells by calculating their response to the fluid flow

The primary cilium which is an organelle in nearly every cell in the vertebrate body extends out of the cell surface like an antenna and is known as cell sensor of mechanical and chemical stimuli. In previous numerical simulations, researchers modeled this organelle as a cantilevered beam attached to the cell surface. In the present study, however, we present a novel model that accommodates for...

تعیین میزان رضایت بیماران بستری از بیمارستانها: مرور نظام مند و متاآنالیز

Background: Patients are the raison d'etre of the hospitals therefore satisfying their needs and expectations is one of the most important duties of the hospitals. Consequently in recent decades patient satisfaction has been considered as a reliable measure for studying the quality of care and treatment. Hence in the present study, documents related to patient satisfaction in Iran was surveyed ...

The dynamic cilium in human diseases Anna D ' Angelo 1 and

Cilia are specialized organelles protruding from the cell surface of almost all mammalian cells. They consist of a basal body, composed of two centrioles, and a protruding body, named the axoneme. Although the basic structure of all cilia is the same, numerous differences emerge in different cell types, suggesting diverse functions. In recent years many studies have elucidated the function of 9...

Olanzapine Overdose in a Pin Point Pupil with Altered Sensorium

Background:Olanzapine is a highly tolerable and easily affordable atypical antipsychotic drug which has been commonly prescribed in both inpatient and outpatient settings for several mental disorders. Olanzapine overdose is commonly seen in psychiatric patients, who attempt suicide by intoxicating themselves with their own prescribed medications. Increased olanzapine use is associated with incr...